Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

Search Within Results

631 – 645 of 4,235 results

631

eMolecules 2105938-35-8 | N2,N6-Dicyanopyridine-2,6-bis(carboximidamide) | Ambeed213.204 | C9H7N7 | 97.000 | N=C(NC#N)c1cccc(n1)C(=N)NC#N | 1g | 845535526

N2,N6-Dicyanopyridine-2,6-bis(carboximidamide) | Ambeed | 2105938-35-8213.204 | C9H7N7 | 97.000 | N=C(NC#N)c1cccc(n1)C(=N)NC#N | 1g | 845535526

Pricing & Availability

632

eMolecules 5622-36-6 | methyl 2-(quinolin-6-yl)acetate | Pharmablock - Stock | MFCD04038669 | 201.225 | C12H11NO2 | 97.000 | COC(=O)Cc1ccc2ncccc2c1 | 1g | 415696918

methyl 2-(quinolin-6-yl)acetate | Pharmablock - Stock | 5622-36-6 | MFCD04038669 | 201.225 | C12H11NO2 | 97.000 | COC(=O)Cc1ccc2ncccc2c1 | 1g | 415696918

Pricing & Availability

633

Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | 144.17 | 1 ML

2-Aminoquinoline (2-Quinolinamine) is a promising compound as a bioavailable nNOS inhibitor. It exhibits antiviral activity against the vaccinia virus and has potential for the research of antineurodegenerative agents. However, it suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets.

Bioavailable nNOS inhibitor
Antiviral activity against vaccinia virus
Potential for antineurodegenerative agent research
Low human nNOS inhibition
Low selectivity versus human eNOS
Significant binding to other CNS targets

Pricing & Availability

634

eMolecules 4965-36-0 | 7-Bromoquinoline | Ambeed | MFCD03695823 | 208.058 | C9H6BrN | 98.000 | Brc1ccc2cccnc2c1 | 5g | 490534630

7-Bromoquinoline | Ambeed | 4965-36-0 | MFCD03695823 | 208.058 | C9H6BrN | 98.000 | Brc1ccc2cccnc2c1 | 5g | 490534630

Pricing & Availability

635

Medchemexpress LLC L-Cystathionine dihydrochloride (Standard) | 61125-50-6 | 99.9% | 295.18 | 10 MG

L-Cystathionine dihydrochloride (Standard) is an analytical standard that is also a nonprotein thioether and a key amino acid linked to the metabolic state of sulfur-containing amino acids. It offers protection against Homocysteine-induced mitochondria-dependent apoptosis in vascular endothelial cells (HUVECs), indicating an important role in cardiovascular protection. This product is intended for research and analytical applications.

Analytical standard for L-Cystathionine dihydrochloride.
Used for research and analytical applications.
Nonprotein thioether.
Key amino acid in sulfur-containing amino acid metabolism.
Protects against Homocysteine-induced mitochondria-dependent apoptosis of HUVECs.
Plays a significant role in cardiovascular protection.
Suitable for qualitative, quantitative, and methodological research experiments using techniques like HPLC, GC, and MS.

Pricing & Availability

636

eMolecules 1255942-06-3 | DBCO-AMINE | AstaTech | MFCD22380759 | 276.339 | C18H16N2O | 95.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 1g | 602855722

DBCO-AMINE | AstaTech | 1255942-06-3 | MFCD22380759 | 276.339 | C18H16N2O | 95.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 1g | 602855722

Pricing & Availability

637

Medchemexpress LLC 1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride | 1620278-72-9 | MFCD31657341 | 99.7% | 432.39 g/mol | C22H27Cl2N5 | 1 ML

TLR7/8 agonist 1 dihydrochloride is a dual-agonistic imidazoquinoline research compound that activates toll-like receptors 7 and 8 to induce innate immune responses. It is used in cell-based assays and in vivo studies to stimulate immune signaling and can serve as a derivatizable precursor for covalent labeling while retaining biological activity.

Dual agonist of toll-like receptors 7 and 8, inducing innate immune signaling.
Low-nanomolar agonistic potency (≈50 nM for TLR7, ≈55 nM for TLR8).
Available as a DMSO solution for convenient dosing in cell assays.
Suitable for use in cell-based and in vivo immunostimulatory studies.
Precursor amenable to covalent modification without significant loss of activity.
Stable when stored sealed at 4°C; in solution recommended -80°C for long-term storage.

Pricing & Availability

638

eMolecules 578-68-7 | Ambeed | 4-Aminoquinoline | 10g | 552659467 | A224551 | MFCD00463448 | 144.177 | C9H8N2

Ambeed | 4-Aminoquinoline | 10g | 552659467 | A224551 | 578-68-7 | MFCD00463448 | 144.177 | C9H8N2

Pricing & Availability

639

Apexbio Technology LLC Mycophenolate Mofetil 128794-94-5 200mg

Mycophenolate Mofetil (128794-94-5) is a small-molecule inhibitor targeting inosine monophosphate dehydrogenase (IMPDH) isoforms I and II It is designed to selectively and reversibly inhibit IMPDH thereby disrupting de novo guanosine nucleotide biosynthesis Mycophenolate Mofetil exerts its biological activity primarily through non-competitive inhibition of IMPDH blocking the conversion of inosine monophosphate (IMP) to xanthosine monophosphate (XMP) In in vitro studies Mycophenolate Mofetil demonstrates inhibitory activity with IC50 values of 39 nM and 27 nM for IMPDH I and II respectively Based on these pharmacological properties Mycophenolate Mofetil holds research potential in studies on immunology purine metabolism regulation cell proliferation transplant rejection and autoimmune disease models

Pricing & Availability

640

Medchemexpress LLC SPP-86 | 1357349-91-7 | 99.9% | 277.32 | 100 MG

SPP-86 is a potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM. It inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling, and also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells. This compound is a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Potent and selective cell permeable inhibitor of RET tyrosine kinase, with an IC50 of 8 nM.
Inhibits RET-induced phosphatidylinositide 3-kinases (PI3K)/Akt and MAPK signaling.
Inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells.
Click chemistry reagent, containing an alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups.

Pricing & Availability

641

Sigma Aldrich Fine Chemicals Biosciences 8-Quinolinol puriss. p.a., ACS reagent, reag. Ph. Eur., >=99% (perchloric acid titration) | 148-24-3 | MFCD00006807 | 100G

Pricing & Availability

642

Medchemexpress LLC Lenvatinib | 417716-92-8 | 99.8% | 1 G

Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor. It inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, demonstrating potent antitumor activities. This compound shows antiproliferative activity and growth inhibition in various cell lines.

Inhibits VEGFR2, VEGFR3, and VEGFR1
Inhibits PDGFRα, PDGFRβ, and FGFR1
Inhibits KIT and RET
Demonstrates antiproliferative activity
Available as a solid form

Pricing & Availability

643

Medchemexpress LLC Olmutinib | 1353550-13-6 | 99.5% / 99.9% | 486.59 | 200 MG

Olmutinib is an orally active and irreversible third-generation EGFR tyrosine kinase inhibitor. It binds to a cysteine residue near the kinase domain and is used for Non-Small Cell Lung Cancer (NSCLC). This product is for research use only.

Orally active
Irreversible third-generation EGFR tyrosine kinase inhibitor
Binds to a cysteine residue near the kinase domain
Used for Non-Small Cell Lung Cancer (NSCLC)
For research use only

Pricing & Availability

644

Medchemexpress LLC Apalutamide | 956104-40-8 | 99.9% | 477.43 | 200 MG

Apalutamide is a potent and competitive antagonist of the androgen receptor (AR), binding to it with an IC50 of 16 nM. It is intended for research use.

Exhibits low micromolar affinity (IC50 3 μM) for the GABAA receptor, potentially antagonizing GABAA at therapeutic dose levels.
Targets the AR ligand-binding domain, preventing AR nuclear translocation, DNA binding, and transcription of AR gene targets.
Shows low systemic clearance, high oral bioavailability, and a long plasma half-life in both mouse and dog, supporting once-daily oral dosing.
Achieves increased steady-state plasma levels in repeat-dose studies, resulting in high C24hr levels and low peak:trough ratios (2.5).
Demonstrated significant tumor-volume reduction in castrate male mice bearing LNCaP/AR xenograft tumors.

Pricing & Availability

645

Apexbio Technology LLC TAK-901 934541-31-8 200mg

TAK-901 (CAS 934541-31-8) is a small-molecule inhibitor primarily targeting Aurora B kinase with reported IC50 values of 0 0017 M for Aurora-B/INCENP and 0 021 M for Aurora-A/TPX2 Derived from an azacarboline kinase hinge-binding chemotype TAK-901 demonstrates time-dependent selective inhibition of Aurora B suppressing histone H3 phosphorylation and inducing polyploidy in vitro It inhibits proliferation across a range of human cancer cell lines (40 500 nM) and additionally targets kinases such as FLT3 and FGFR2 in cells In preclinical rodent xenograft models TAK-901 reduces tumor growth and induces complete regression in ovarian cancer models A phase I clinical trial has evaluated its dosing and pharmacokinetic characteristics in patients with advanced solid tumors and lymphomas

Pricing & Availability

Quinolines and derivatives

Filtered Search Results

Narrow Results

Medchemexpress LLC 2-Aminoquinoline | 580-22-3 | 144.17 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC L-Cystathionine dihydrochloride (Standard) | 61125-50-6 | 99.9% | 295.18 | 10 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 1-(4-(aminomethyl)benzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine dihydrochloride | 1620278-72-9 | MFCD31657341 | 99.7% | 432.39 g/mol | C22H27Cl2N5 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Mycophenolate Mofetil 128794-94-5 200mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SPP-86 | 1357349-91-7 | 99.9% | 277.32 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Lenvatinib | 417716-92-8 | 99.8% | 1 G Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Olmutinib | 1353550-13-6 | 99.5% / 99.9% | 486.59 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Apalutamide | 956104-40-8 | 99.9% | 477.43 | 200 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC TAK-901 934541-31-8 200mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More